The best pre-workout products can enhance energy, power, and cognition as you… run?
Although you might not associate your favorite gym juice with longer distances and faster paces, pre-workout powders aren’t just for bodybuilders. You may find that the best pre-workout for running lands in your training bag alongside intra-workout carbohydrates and a post-recovery protein shake.
As a registered dietitian, I teamed up with our expert product testers—from a triathlete to a certified personal trainer to a USA Weightlifting L-2 coach—to evaluate dozens of pre-workouts for this list. We go the extra mile and analyze factors such as:
- Formulation: Does it include scientifically-backed ingredients and dosages?
- Third-party testing: Can we trust that the label is accurate and the product is pure?
- Taste: Is it enjoyable, or at least drinkable, with multiple flavor options?
- Price per serving: Does it align with the market average, or at least provide value?
While you’ll run into more details about our methodology ahead, let’s start strategizing your newest pre-run ritual. On your mark, get set, let’s go!
Medical disclaimer: This article is intended for educational and informational purposes only. It is not intended as a substitute for medical advice. For health advice, contact a licensed healthcare provider.
Best Pre-Workout for Running
- Best Pre-Workout for Running Overall: Transparent Labs Stim-Free
- Best Natural Pre-Workout for Running: Legion Pulse
- Best Stim-Free Pre-Workout for Running: 1st Phorm Endura-Formance
- Best Budget Pre-Workout for Running: Nutricost Pre-X Pre-Workout
- Best Sugar-Free Pre-Workout for Running: Alyne Pre-Workout
Best Pre-Workout for Running Overall: Transparent Labs Stim-Free
Good for: Runners chasing athletic performance benefits without stimulants
Transparent Labs Stim-Free Pre-Workout is an uncaffeinated pre-workout powder that will not give you the jitters or tingling commonly associated with pre-workout supplements. This pre-workout contains a blend of citrulline malate, beta-alanine, L-tyrosine, taurine, and elevATP, a compound claimed to increase ATP activity in muscle cells.
What our tester says:
“I felt focused at all times and there was no energy crash at the end of my workout.”
Best Natural Pre-Workout for Running: Legion Pulse
Good for: People looking for a 100% all-natural formulation with (or without) caffeine
Formulated with all-natural ingredients, each of which are present at a high level, Legion Pulse’s stim-free pre-workout formula is a fan favorite. If you’re trying to avoid artificial flavors and chemicals, this may be a good choice.
What our tester says:
“While it mixes well, the Blue Raspberry does have a bitter taste and an unpleasant aftertaste.”
Best Stim-Free Pre-Workout for Running: 1st Phorm Endura-Formance
Good for: Those looking for an effective and innovative pre-workout without caffeine
Endura-Formance is formulated with all the key ingredients one would look for in a pre-workout drink. While the taste is not for everyone, most users experienced improved performance at the gym.
What our tester says:
“The flavor is fantastic: Not too sweet, yet slightly tart. Plus, there’s no weird aftertaste.”
Best Budget Pre-Workout for Running: Nutricost Pre-X Pre-Workout
Good for: Those who want an effective pre-workout without running into budgeting troubles
Nutricost Pre-X is an affordable pre-workout at about $1 per serving. There are five flavors to choose from, each with a light and refreshing taste. Each serving contains 300 milligrams of caffeine, which is equivalent to about 3 cups of coffee.
What our tester says:
“With this one, even two hours after taking it, I didn’t have a comedown, crash, or feel tired. I could still work really hard through my sessions.”
Best Sugar-Free Pre-Workout for Running: Alyne Pre-Workout
Good for: Runners who want a natural pre-workout without added sugars and artificial sweeteners
Other Pre-Workouts for Running We Researched
There are countless pre-workouts, and several can support your runs just like our top six picks. Here are a few more worth considering:
- Genius Pre-Workout: Touted for its hyper-palatable flavors and cognitive benefits without caffeine.
- Optimum Nutrition Gold Standard Pre-Workout: Receives positive reviews for its standard yet effective (slightly caffeinated) formula, great flavors and solubility, and value.
- Transparent Labs BULK Pre-Workout: Similar to Transparent Labs Stim-Free, but contains extra ingredients like caffeine (albeit less than 200 milligrams) and branched-chain amino acids24 (BCAAs) to support post-exercise recovery and reduce muscle soreness.

How We Picked and Tested the Best Pre-Workout for Running
As seasoned triathletes and avid runners, we’re diligent and intentional about how we narrowed down our list. We lean on our trusty GGR supplement testing methodology to make our selection after analyzing these factors:
Efficacious Ingredients and Doses
A pre-workout is only as good as its formulation, so we seek products with evidence-based ingredients and doses that research supports. We also prioritized effective ingredients for running performance9, including beta-alanine, caffeine, and taurine.
Flavor
Some runners might savor the nostalgic taste of Fruit Punch, while others might enjoy the tropical vibes of Strawberry Margarita. Our top picks include diverse flavors to cater to this wide range of preferences.
Solubility
Nobody likes a clumpy pre-workout drink, so we always consider how well it dissolves and blends. We aim to choose smooth, consistent options without vigorous, lengthy mixing times.
Cost
We strongly believe cost should not be between you and your fitness journey. That’s why we offer diverse products to fit every budget, ensuring you get the fuel you need to reach your goals without compromising value.

Customer Reviews and Experience
The GGR team rigorously tests and reviews every product we recommend, but we also want to ensure that other customers have a positive experience. We also analyze customer reviews from third-party sites like Amazon to maintain objectivity, reducing potential biases from brand sites.
Side Effects
Common and potential side effects of pre-workouts include digestive issues, nausea, jitters, tingling, and shaking, which can make for an unpleasant training session. Our GGR expert testers assess these side effects through personal use and customer reviews, giving preference to products with minimal or no adverse effects.
Third-Party Testing
Has the product undergone testing by an independent third-party lab? If it claims to be gluten-free, does it bear the Certified Gluten-Free label? Given the loose regulations surrounding supplements, we prioritize and diligently review the verifications and certifications of every product we test.
Benefits of Pre-Workout for Running
Incorporating a pre-workout supplement into your running routine can enhance various aspects of your training. Here’s how:
- Increases energy: The energy-boosting properties of caffeine17 can improve both sprint and aerobic performances, helping you push through tough workouts.
- Promotes hydration: Mixing pre-workout supplements with at least 6 ounces of water helps you stay hydrated and get an extra dose of fluids. Some pre-workout products include electrolytes1, further enhancing hydration.
- Enhances exercise performance and recovery: Key ingredients like beta-alanine4 and betaine6 improve muscular endurance and power, optimizing your training sessions. Additionally, citrulline malate8 and other nitric oxide boosters increase the delivery of oxygen and nutrients to muscles, enhancing performance and recovery.
- Increases focus: Stimulants and nootropics12 in pre-workouts enhance focus, keeping you dialed into your training. Combining caffeine and L-theanine18 in some products can amplify cognitive benefits while reducing the chance of jitters.
Dosing and Interactions
Consult your doctor or dietitian before taking pre-workout, especially if you take prescription medications, as some ingredients may cause harmful interactions. Additionally, individuals with cardiovascular disease or hypertension should be cautious, as caffeine can elevate heart rate and other ingredients may increase blood flow.

Third-Party Testing
Since dietary supplements aren’t FDA-regulated, it’s crucial for an independent third-party lab to verify that a pre-workout formula matches its label, especially for athletes subject to drug testing. Equally important is transparency—seek companies that provide Certificates of Analysis (COAs), avoid proprietary blends, and are open about their ingredients and purposes.
Buying Guide: What to Look for in Pre-Workouts for Running
Whether you’re beginning your pre-workout journey or simply want to try something new, here’s what to look for in a pre-workout for running to best support your training:
Formulation
Pre-workout formulations can significantly vary, so choose one that aligns with your training goals. Consider what you need and want, whether electrolytes for hot or extended runs, caffeine for an energy boost, or nootropics to improve mental focus.
Also, consider any other supplements you’re already using. For example, you might not need a pre-workout with extra electrolytes if you already have a favorite sports drink.
Flavor
Choose a flavor you’ll enjoy, as palatability encourages consistent fluid intake. If you’re deciding between two pre-workouts, consider trying the one with more flavor options, like Legion Pulse over Alyne. Legion’s wide range of flavors gives you more choices if you enjoy the effects but not the initial flavor, unlike Alyne, which offers only one option.
Price
When budgeting for a pre-workout supplement, consider the other essentials you need or want for running, such as shoes, apparel, and recovery tools. Most high-quality running shoes last between 300 to 500 miles, or up to six months if you run an average of 20 miles per week, so the cost can quickly add up as the miles do.
Certifications
We recommend prioritizing third-party-tested supplements and certifications that align with your specific needs. For instance, competitive athletes subject to drug testing should opt for products certified free of banned substances, like those verified by Informed Sport.
Experts Who Contributed to This Article
FAQs About Pre-Workouts for Running
Are pre-workouts good for running?
Pre-workouts can benefit running thanks to ingredients that enhance athletic performance. They often contain caffeine, which boosts energy levels, beta-alanine to improve muscular endurance, and electrolytes to aid hydration. These components can collectively help you run longer and feel more energized during your sessions.
What is the best pre-workout for long-distance runners?
While pre-workouts should complement, not replace, running fuel for long runs, following some general guidelines can help you choose the right one. Look for options that include essential electrolytes like sodium and potassium, aiming for at least 300 milligrams per hour of exercise. Additionally, common pre-workout ingredients like caffeine, L-theanine, and beta-alanine can boost energy, endurance, and focus to push through those longer runs.
What is the best supplement to take before running?
Choosing the best supplement to take before running depends on your specific needs and the nature of your training session. If you’re looking for a quick energy boost, a carb-rich gel is ideal for convenience and efficiency. For long-distance runs or hot weather conditions, a high-dose electrolyte powder like LMNT can help you maintain proper hydration and prevent cramping. However, if your nutrition and hydration are already well-balanced, you might not need any supplement, though an effectively dosed pre-workout could be just what you need for an extra kick.
Is it good to take C4 before running?
Taking C4 before running can be beneficial due to its key ingredients—like caffeine, beta-alanine, and other ergogenic compounds—that help enhance endurance and reduce fatigue. However, some doses are low, including L-citrulline to improve blood flow, but its arginine25 content may compensate for this as a nitric oxide booster.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any diseases.
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